Coro1a - coronin 1A

Predicted to enable several functions, including cytoskeletal protein binding activity; protein C-terminus binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including natural killer cell degranulation; negative regulation of actin nucleation; and phagolysosome assembly. Predicted to act upstream of or within several processes, including early endosome to recycling endosome transport; nerve growth factor signaling pathway; and regulation of organelle organization. Predicted to be located in several cellular components, including actin filament; cytoplasmic vesicle; and immunological synapse. Predicted to be part of protein-containing complex. Predicted to be active in stereocilium tip. Predicted to colocalize with cortical actin cytoskeleton. Human ortholog(s) of this gene implicated in coronin-1A deficiency. Orthologous to human CORO1A (coronin 1A). [provided by Alliance of Genome Resources, Apr 2022]