Enables lipase activity. Acts upstream of or within cholesterol homeostasis; cholesterol metabolic process; and cholesterol transport. Located in extracellular space. Is expressed in liver and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; familial combined hyperlipidemia; glucose metabolism disease (multiple); obesity; and peripheral vascular disease. Orthologous to human LIPC (lipase C, hepatic type). [provided by Alliance of Genome Resources, Apr 2022]