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中文人类
CYP1A2 - Cytochrome P450 Family 1 Subfamily A Member 2
Alias:
CP12
CYPIA2
P3-450
P450(PA)
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这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。这个基因编码的蛋白质定位在内质网，并且由其表达受到一些多环芳烃（PAHs）的诱导，其中一些存在于香烟烟雾中。这种酶的内源底物尚不清楚；然而，它能够将一些PAHs代谢成致癌的中间产物。这种酶的其他外来底物包括咖啡因、黄曲霉素B1和醋氨酚。这个基因的转录本在3'非翻译区含有四个Alu序列，两侧是直接重复。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYP1A2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
