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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Foxa2 - forkhead box A2
Alias:
Hnf3b
Tcf3b
Hnf-3b
Tcf-3b
HNF3beta
HNF3-beta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及染色质结合活性。参与多个过程,包括葡萄糖检测的负调控;葡萄糖激酶活性的负调控;以及DNA模板转录的调控。在多个过程的上游或内部发挥作用,包括动物器官发育;脊索动物胚胎发育;以及神经元分化的调控。位于细胞核中。是转录调控复合物的一部分。在几个结构中表达,包括中枢神经系统;内胚层;生殖泌尿系统;肠道;和呼吸系统。这个基因的人类同源物与2型糖尿病有关。与人类FOXA2(翼状翅盒A2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:15376
ENSEMBL:ENSMUSG00000037025
UNIPROT:P35583
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
15376
3
2
4093 bp
48.50
16
18
Foxa2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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