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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Nr4a1 - nuclear receptor subfamily 4, group A, member 1
Alias:
Hmr
N10
TR3
Gfrp
Hbr1
NP10
TIS1
GFRP1
Hbr-1
NGFIB
nur77
NGFI-B
NUR77-1
NUR77-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;具有相同的蛋白质结合活性;以及序列特异性的DNA结合活性。参与细胞对促皮质素释放激素刺激的应答;脂肪细胞分化;以及负调控细胞周期。在几个过程的上游或内部发挥作用,包括RNA聚合酶II的正调控转录;凋亡过程的调控;以及骨骼肌细胞分化。位于细胞核中。是转录调节复合物的一部分。在几个结构中表达,包括骨骼;泌尿系统;血细胞系统;神经系统;下颌下腺原基。与人类的NR4A1(核受体亚家族4A成员1)正同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:15370
ENSEMBL:ENSMUSG00000023034
UNIPROT:P12813
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
15370
7
9
20894 bp
64.74
6
13
Nr4a1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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