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中文人类
CYBB - Cytochrome B-245 Beta Chain
Alias:
CGD
CGDX
NOX2
IMD34
AMCBX2
GP91-1
GP91PHOX
p91-PHOX
GP91-PHOX
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细胞色素b（-245）由细胞色素bα（CYBA）和β（CYBB）链组成。它被提议作为吞噬细胞杀菌氧化酶系统的主要组成部分。CYBB缺乏是与慢性肉芽肿病（CGD）相关的五种描述的生物化学缺陷之一。在这个紊乱中，吞噬细胞NADPH氧化酶的活性降低；中性粒细胞可以吞噬细菌，但不能在吞噬性空泡中杀死它们。杀死缺陷的原因是细胞呼吸不能增加，从而导致激活的氧气不能输送到吞噬性空泡中。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CYBB Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Anatomical Category
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Mutations
Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
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References Literature
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