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中文小鼠
Hmgcr - 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Alias:
Red
HMG-CoAR
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激活羟甲基戊酸辅酶A还原酶(NADPH)活性。参与淀粉样蛋白清除的负调控；蛋白质分解代谢过程的负调控；和蛋白质分泌的负调控。在胆固醇生物合成过程的上游或内发挥作用；MAP激酶活性的负调控；和视觉学习。预测位于内质网内。预测在内质网膜和过氧化物体内活性。在几个结构中表达，包括触肢；鳃弓；中枢神经系统；前肢芽；和神经节。这个基因的人类同源物涉及几种疾病，包括哮喘；冠状动脉疾病(多种)；痴呆；糖尿病(多种)；和神经退行性疾病(多种)。与人类HMGCR(3-羟基-3-甲基戊酸辅酶A还原酶)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hmgcr Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
