Hipk2 - homeodomain interacting protein kinase 2

1. Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; protein serine/threonine kinase activity; and transcription corepressor activity. 激活RNA聚合酶II特异性的DNA结合转录因子结合活性；蛋白质丝氨酸/苏氨酸激酶活性；以及转录核心抑制子活性 2. Contributes to transcription coactivator activity. 参与转录共激活子活性 3. Involved in several processes, including camera-type eye morphogenesis; protein phosphorylation; and regulation of transcription, DNA-templated. 参与多个过程，包括相机型眼睛形态发生；蛋白质磷酸化；以及基于DNA模板的转录调控 4. Acts upstream of or within several processes, including adult walking behavior; cell surface receptor signaling pathway; and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. 在多个过程的上游或内部发挥作用，包括成年行走行为；细胞表面受体信号通路；以及响应p53类介体的DNA损伤的内源性凋亡信号通路 5. Located in cytoplasm and nucleus. 位于细胞质和细胞核中 6. Part of RNA polymerase II transcription regulator complex. 是RNA聚合酶II转录调节复合物的一部分 7. Is expressed in several structures, including alimentary system; central nervous system; metanephros; paraxial mesenchyme; and sensory organ. 在多个结构中表达，包括消化系统；中枢神经系统；肾单位；旁中胚层；和感光器 8. Orthologous to human HIPK2 (homeodomain interacting protein kinase 2). 与人类的HIPK2（同源域相互作用蛋白激酶2）正交 以上信息是根据Alliance of Genome Resources（基因组资源联盟）2022年4月的数据提供的