小鼠

Hgf - hepatocyte growth factor

Alias:
SF
NK1
NK2
HGF/SF
SF/HGF
C230052L06Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个蛋白质,该蛋白质与肝细胞生长因子受体结合,以调节多种细胞和组织类型的细胞生长、细胞运动和形态发生。编码的前原原蛋白在蛋白水解过程中被加工成多个蛋白质产物,包括肝细胞生长因子的α和β链,它们异二聚形成成熟的活性蛋白质。尽管这种蛋白质是丝氨酸蛋白酶肽酶S1家族的成员,但它缺乏肽酶活性。这个基因的纯合子敲除小鼠由于胎盘和肝脏发育受损而表现出胚胎致死。可选的剪接导致多个转录变异体编码不同的异构体。[由RefSeq,2015年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
6
19
68956 bp
82.94
7
17

Hgf Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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