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中文小鼠
Hesx1 - homeobox gene expressed in ES cells
Alias:
Rpx
HES-1
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具有多种功能，包括DNA结合转录抑制活性，特异性RNA聚合酶II；蛋白质C端结合活性；和蛋白质同源二聚化活性。参与RNA聚合酶II负调控转录。在正则Wnt信号通路的上游或内部具有负作用。参与几个过程，包括ERK1和ERK2级联；动物器官发育；和细胞表面受体信号通路。位于细胞核中。在几个结构中表达，包括早期概念体；胚胎外胚层；胚胎内胚层；泌尿系统；和胸腺。用于研究垂体功能减退和视-顶盖发育不良。该基因的人类同源物与视-顶盖发育不良有关。与人类HESX1（HESX homeobox 1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hesx1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
