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中文小鼠
Herc2 - HECT and RLD domain containing E3 ubiquitin protein ligase 2
Alias:
rjs
jdf2
D15F32S1h
mKIAA0393
D7H15F32S1
D7H15F37S1
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预测能够实现SUMO结合活性；泛素蛋白连接酶活性；以及泛素蛋白连接酶结合活性。参与蛋白酶体介导的泛素依赖性蛋白质降解过程。在精子发生过程中发挥上游或内部作用。位于线粒体内膜上。在几个结构中表达，包括中枢神经系统；神经节；和躯干。这个基因的人类同源物与常染色体隐性非综合征性智力障碍和色素沉着病有关。与人类HERC2（含HECT和RLD结构域的E3泛素蛋白连接酶2）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Herc2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
