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中文人类
ADRA2C - Adrenoceptor Alpha 2C
Alias:
ADRA2L2
ADRARL2
ADRA2RL2
ALPHA2CAR
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阿尔法-2-肾上腺素能受体是G蛋白偶联受体超家族的成员。它们包括3个高度同源的亚型：alpha2A、alpha2B和alpha2C。这些受体在调节来自交感神经和中枢神经系统肾上腺能神经元的神经递质释放方面具有关键作用。小鼠研究表明，alpha2A和alpha2C亚型对于心脏中交感神经和中央去甲肾上腺素能神经元正常突触前递质释放的控制是必需的。alpha2A亚型在高刺激频率下抑制递质释放，而alpha2C亚型在神经活动较低水平上调节神经传递。该基因编码alpha2C亚型，其编码序列和未翻译序列中均无内含子。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ADRA2C Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
