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Ptpn6 - protein tyrosine phosphatase, non-receptor type 6

Alias:
me
hcp
Hcph
Ptp1C
SHP-1
70Z-SHP
SH-PTP1
PTPTY-42
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括磷酸酪氨酸残基结合活性;蛋白质结构域特异性结合活性;以及蛋白质酪氨酸磷酸酶活性。参与睾丸发育;负调控白细胞介素-6的产生;以及负调控肿瘤坏死因子的产生。在几个过程的上游或内部发挥作用,包括造血;蛋白质磷酸化的负调控;以及淋巴细胞激活的调控。位于细胞-细胞连接处。是α-βT细胞受体的组成部分。在几个结构中表达,包括中枢神经系统;视网膜;和胸腺原基。与人类的PTPN6(非受体型蛋白质酪氨酸磷酸酶6)正链同源。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
16
18003 bp
67.56
18
28

Ptpn6 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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