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中文小鼠
Hap1 - huntingtin-associated protein 1
Alias:
HAP-1
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这个基因编码的蛋白质最初被鉴定为一种与HD蛋白huntingtin结合的神经元蛋白质。该蛋白质还与微管蛋白轻链、14-3-3蛋白和Abelson辅助整合位点1蛋白相互作用。该蛋白质参与囊泡和细胞器的细胞内运输，缺乏该蛋白质导致神经元死亡，类似于亨廷顿病中发生的下丘脑变性。已发现这个基因有多个编码不同异型的转录变异体。[由RefSeq，2009年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Hap1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
