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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Hand2 - heart and neural crest derivatives expressed 2
Alias:
Hed
Th2
dHAND
Ehand2
Thing2
bHLHa26
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有蛋白质同二聚化活性,并具有序列特异性的DNA结合活性。参与E-box结合活性。涉及几个过程,包括心脏形态发生;负调控心肌细胞凋亡过程;以及正调控参与流出沟形态发生的Semaphorin-Plexin信号通路。在几个过程的上游或内部发挥作用,包括动物器官发育;负调控成骨细胞分化;以及神经系统发育。位于细胞核中。是转录调节复合物的一部分。在几个结构中表达,包括消化系统;胚胎间充质;生殖泌尿系统;心脏;和后肢指骨。与人类HAND2(心和神经嵴衍生物2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:15111
ENSEMBL:ENSMUSG00000038193
UNIPROT:Q61039
Basic Information
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Transcripts
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Length
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15111
1
2
3535 bp
23.67
15
8
Hand2 Genetics information (+)
GRCm39
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* This data comes from NCBI.
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