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中文人类
CTSD - Cathepsin D
Alias:
CPSD
CLN10
HEL-S-130P
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这个基因编码A1家族肽酶成员。编码的前原蛋白在蛋白水解过程中被加工成多个蛋白质产物。这些产物包括组织蛋白酶D轻链和重链，它们异二聚化形成成熟的酶。这种酶表现出类似胃蛋白酶的活性，在蛋白质的周转和激素及生长因子的蛋白水解激活中发挥作用。这个基因的突变是导致神经元蜡黄素沉积病-10的病因，可能涉及其他几种疾病的病理生理，包括乳腺癌和可能包括阿尔茨海默病。[RefSeq, Nov 2015提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CTSD Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
