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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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小鼠
H2-T22 - histocompatibility 2, T region locus 22
Alias:
27b
T22b
H-2T17
H-2T22
H2-T17
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括14-3-3蛋白结合活性;TAP结合活性;和信号受体结合活性。参与多种过程,包括通过ER途径、TAP非依赖性的内源肽抗原的MHC I类抗原处理和呈递;内源肽抗原的MHC Ib类抗原处理和呈递;以及T细胞介导的细胞毒性的正向调节。位于多种细胞组件中,包括膜器官;细胞表面;和高尔基体。被认为是MHC I类蛋白复合物和MHC Ib类蛋白复合物的一部分。在质膜的外侧和细胞外空间中活性。在几个结构中表达,包括泌尿生殖系统;肠道;呼吸系统;感觉器官;和骨架。该基因的人类同源物涉及哮喘;丙型肝炎;和职业性哮喘。与人类HLA-E(主要组织相容性复合物I类E);HLA-F(主要组织相容性复合物I类F);和HLA-G(主要组织相容性复合物I类G)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:15039
ENSEMBL:ENSMUSG00000056116
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
15039
5
9
5615 bp
Unknown
--
12
H2-T22 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
Strain of Origin
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