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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DUSP18 - Dual Specificity Phosphatase 18
Alias:
DSP18
DUSP20
LMWDSP20
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
双特异性磷酸酶(DUSPs)是I型基于半胱氨酸的蛋白质酪氨酸磷酸酶超家族的一个大型异质子亚群。DUSPs的特点是它们能够去磷酸化酪氨酸和丝氨酸/苏氨酸残基。它们被认为是最重要的信号传导途径的主要调节因子。DUSP18含有共识的DUSP C端催化结构域,但没有DUSPs的MKP(有丝分裂原激活的蛋白激酶磷酸酶)类别的N端CH2结构域(参见MIM 600714)(Patterson等人,2009年总结[PubMed 19228121])。[由OMIM于2009年12月提供]
Related ID:
NCBI:150290
ENSEMBL:ENSG00000167065
HGNC:18484
UNIPROT:Q8NEJ0
OMIM:611446
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
150290
10
2
15825 bp
21.07
15
--
3
7
DUSP18 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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