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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
H2-Q10 - histocompatibility 2, Q region locus 10
Alias:
Q10
Qa10
H2-K1
H-2Q10
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括14-3-3蛋白结合活性;TAP结合活性;和信号受体结合活性。参与多种过程,包括通过ER途径、TAP非依赖性的MHC I类内源肽抗原的抗原加工和呈递;MHC Ib类内源肽抗原的抗原加工和呈递;以及T细胞介导的细胞毒性的正向调节。预测在抗原加工和呈递中起上游或内部作用。位于细胞外空间。在多个结构中表达,包括肝脏;男性生殖腺或器官;和卵巢。该基因的人类同源物涉及几种疾病,包括Stevens-Johnson综合征;哮喘(多种);自身免疫性疾病(多种);眼疾(多种);和内耳疾病(多种)。与几个人类基因正交,包括HLA-E(主要组织相容性复合体I类E);HLA-F(主要组织相容性复合体I类F);和HLA-G(主要组织相容性复合体I类G)。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:15007
ENSEMBL:ENSMUSG00000067235
UNIPROT:P01898
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
15007
1
7
4475 bp
37.25
5
9
H2-Q10 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Acting
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Type
Name
MGI
Strain of Origin
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References Literature
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