小鼠

Gzmb - granzyme B

Alias:
GZB
CCP1
Ctla1
Ctla-1
CCP-1/C11
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码颗粒酶亚家族蛋白质的一员,这是丝氨酸蛋白酶肽酶S1家族的一部分。编码的前原蛋白被自然杀手(NK)细胞和细胞毒性T淋巴细胞(CTLs)分泌,并通过蛋白水解过程生成活性蛋白酶,从而诱导目标细胞凋亡。这种蛋白质还处理细胞因子并降解细胞外基质蛋白,这些作用与慢性炎症和伤口愈合有关。缺乏这个基因功能副本的小鼠表现出免疫细胞介导的细胞溶解受损。[由RefSeq,2016年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
5
3499 bp
27.47
9
14

Gzmb Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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