小鼠

Hspa5 - heat shock protein 5

Alias:
Bip
Sez7
mBiP
Grp78
SEZ-7
Hsce70
baffled
D2Wsu17e
D2Wsu141e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
能够使错误折叠的蛋白质结合活性并结合核糖体。参与几个过程,包括IRE1介导的未折叠蛋白质应答;小脑发育;以及蛋白质泛素化的正向调节。在几个过程的上游或内部发挥作用,包括细胞对白细胞介素-4的反应;转化生长因子β受体信号通路负向调节;以及毒素运输。位于几个细胞组件中,包括细胞表面;内质网;以及内质网-高尔基中间复合体。是内质网分子伴侣复合物的一部分。在几个结构中表达,包括消化系统;大脑;眼睛;生殖泌尿系统;以及肌肉骨骼系统。该基因的人类同源物与多巴胺β-羟化酶缺乏症有关。与人类HSPA5(热休克蛋白家族A(Hsp70)成员5)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
9
4440 bp
72.42
10
31

Hspa5 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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