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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Nr3c1 - nuclear receptor subfamily 3, group C, member 1
Alias:
GR
Grl1
Grl-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括糖皮质激素受体活性;相同的蛋白质结合活性;以及蛋白激酶结合活性。参与RNA聚合酶II正向调节pri-miRNA转录。在几个过程的上游或内部发挥作用,包括腺体发育;糖皮质激素受体信号通路;以及细胞生物合成过程的调节。位于细胞质;膜;和细胞核中。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;肺;和感觉器官。用于研究原发性醛固酮增多症。该基因的人类同源物涉及几种疾病,包括厌食症;多种肺病;重度抑郁症;肥胖症;和肾细胞癌。与人类NR3C1(核受体亚家族3C组C成员1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14815
ENSEMBL:ENSMUSG00000024431
UNIPROT:P06537
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14815
16
9
108888 bp
87.16
25
29
Nr3c1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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IF
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