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中文人类
TICAM1 - TIR Domain Containing Adaptor Molecule 1
Alias:
TRIF
IIAE6
MyD88-3
PRVTIRB
TICAM-1
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这个基因编码一个含有Toll/白介素-1受体(TIR)同源结构的衔接蛋白，这是一个细胞内信号传导结构域，可介导Toll样受体(TLRs)与信号传导成分之间的蛋白质-蛋白质相互作用。该蛋白参与针对入侵病原体的天然免疫。它特异性地与其他Toll样受体3相互作用，但不与其他TLRs相互作用，这种关联通过激活核因子kappa-B在抗病毒免疫应答过程中调节干扰素-β的诱导。这个基因的突变与感染诱导的急性脑病相关。[RefSeq,2020年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TICAM1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
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Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
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