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Gria2 - glutamate receptor, ionotropic, AMPA2 (alpha 2)

Alias:
GluA2
Glur2
GluR-B
Glur-2
gluR-K2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
谷氨酸受体是哺乳动物大脑中主要的兴奋性神经递质受体,在各种正常的神经生理过程中被激活。这个基因产物属于一个对α-氨基-3-羟基-5-甲基-4-异氧唑丙酸(AMPA)敏感的谷氨酸受体家族,并作为配体激活的阳离子通道发挥作用。这些通道由4个相关亚单位组装而成,分别是Gria1-4。这个基因编码的亚单位(Gria2)在第二个跨膜结构域内受到RNA编辑(CAG->CGG; Q->R)的影响,这被认为使通道对Ca(2+)不可渗透。这个基因的替代剪接,导致编码不同异型体的转录变异体(包括在信号传导特性上有所差异的翻转和翻转异型体)已经被注意到。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
6
16
122778 bp
Unknown
20
--

Gria2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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