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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ADRA1A - Adrenoceptor Alpha 1A
Alias:
ADRA1C
ADRA1L1
ALPHA1AAR
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
阿尔法-1-肾上腺素能受体(alpha-1-ARs)是G蛋白偶联受体超家族的成员。它们激活有丝分裂反应并调节许多细胞的生长和增殖。有3个alpha-1-AR亚型:alpha-1A、-1B和-1D,它们都通过Gq/11家族的G蛋白信号,并且不同的亚型表现出不同的激活模式。这个基因编码alpha-1A肾上腺素能受体。这个基因的可变剪接产生了四个转录变异体,它们编码具有不同C端的不同四个体,但具有相似的配体结合特性。[由RefSeq,2008年7月提供]
Related ID:
NCBI:148
ENSEMBL:ENSG00000120907
HGNC:277
UNIPROT:P35348
OMIM:104221
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
148
12
3
119230 bp
51.49
23
--
9
17
ADRA1A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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References Literature
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