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中文人类
NLRP4 - NLR Family Pyrin Domain Containing 4
Alias:
CT58
PAN2
RNH2
NALP4
PYPAF4
CLR19.5
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这个基因编码的蛋白质是核苷酸结合和亮氨酸富集重复受体（NLR）家族的一员，预测含有N-末端吡嗪效应子结构域（PYD），中央位置的核苷酸结合和寡聚化结构域（NACHT）和C-末端亮氨酸富集重复序列（LRR）。这个基因产物已被证明在蛋白质与其NACHT结构域相互作用的情况下，作为自噬和I型干扰素信号通路的不良调控者的角色。PYD结构域也被证明在抑制NF-kB（激活的B细胞的核因子kappa轻链增强子）中具有重要意义。[由RefSeq提供，2016年12月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NLRP4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
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