Got1 - glutamic-oxaloacetic transaminase 1, soluble

Enables L-aspartate:2-oxoglutarate aminotransferase activity and phosphatidylserine decarboxylase activity. Acts upstream of or within several processes, including dicarboxylic acid metabolic process; fatty acid homeostasis; and glycerol biosynthetic process. Located in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in amyloidosis; amyotrophic lateral sclerosis; pancreatic ductal adenocarcinoma; and transient cerebral ischemia. Orthologous to human GOT1 (glutamic-oxaloacetic transaminase 1). [provided by Alliance of Genome Resources, Apr 2022]