人类

ADRA1B - Adrenoceptor Alpha 1B

Alias:
ADRA1
ALPHA1BAR
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
阿尔法-1-肾上腺素能受体(alpha-1-ARs)是G蛋白偶联受体超家族的成员。它们激活有丝分裂反应并调节许多细胞的生长和增殖。有3个alpha-1-AR亚型:alpha-1A、-1B和-1D,它们都通过Gq/11家族的G蛋白信号,并且不同的亚型显示出不同的激活模式。这个基因编码alpha-1B-肾上腺素能受体,当转染到NIH 3T3成纤维细胞和其他细胞系中时,它引发肿瘤转化。因此,这个正常的细胞基因被识别为一个原癌基因。这个基因由2个外显子和至少20kb的大单个大内切子组成,它们中断了编码区域。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
2
124120 bp
56.84
23
--
4
7

ADRA1B Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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