Gnaq - guanine nucleotide binding protein, alpha q polypeptide

Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activator activity; and alkylglycerophosphoethanolamine phosphodiesterase activity. Involved in several processes, including cranial skeletal system development; endothelin receptor signaling pathway; and multicellular organism aging. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; maternal behavior; and neuron development. Located in cell body; dendrite; and membrane. Is expressed in several structures, including central nervous system; gonad; heart; intestine smooth muscle circular layer; and retina. Used to study congestive heart failure and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q). [provided by Alliance of Genome Resources, Apr 2022]