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中文小鼠
Glrb - glycine receptor, beta subunit
Alias:
spa
Glyrb
spastic
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这个基因编码甘氨酸受体的β亚基，该五聚体由α和β亚基组成。受体作为神经递质门控离子通道发挥作用，通过结合甘氨酸到受体上，增加氯离子传导而产生超极化作用。这个基因在新生儿和成年小鼠的中枢神经系统中广泛转录。在人类中，这个基因的突变导致惊跳病，也称为遗传性惊厥症或先天性僵硬人综合症，这是一种以肌肉僵硬为特征的疾病。可变剪接导致多个转录变异体。[由RefSeq，2016年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Glrb Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
