Gjb4 - gap junction protein, beta 4

Enables gap junction channel activity. Involved in cell-cell signaling and gap junction-mediated intercellular transport. Acts upstream of or within olfactory behavior and sensory perception of smell. Is integral component of plasma membrane. Part of connexin complex. Is expressed in early conceptus; gut; male reproductive gland or organ; metanephros; and skin. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and erythrokeratodermia variabilis et progressiva 2. Orthologous to human GJB4 (gap junction protein beta 4). [provided by Alliance of Genome Resources, Apr 2022]