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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
VCAN - Versican
Alias:
WGN
ERVR
GHAP
PG-M
WGN1
CSPG2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是agrecan/versican蛋白聚糖家族的成员。所编码的蛋白质是一种大型的硫酸软骨素蛋白聚糖,是细胞外基质的主要组成部分。这个蛋白质参与细胞粘附、增殖、分化、迁移和血管生成,并在组织形态发生和维护中扮演重要角色。这个基因的突变是导致瓦格纳综合症1型的原因。已经发现这个基因有多个转录变异体,编码不同的异构体。[由RefSeq,2009年8月提供]
Related ID:
NCBI:1462
ENSEMBL:ENSG00000038427
HGNC:2464
UNIPROT:P13611
OMIM:118661
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1462
4
15
110559 bp
372.82
1723
3
14
23
VCAN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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