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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CSNK2A2 - Casein Kinase 2 Alpha 2
Alias:
CK2A2
CSNK2A1
CK2alpha'
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码蛋白激酶酶酸的α’, 或α2催化亚基,即酪蛋白激酶2(CK2)。酪蛋白激酶2是一种对酸性蛋白质如酪蛋白进行磷酸化的丝氨酸/苏氨酸蛋白激酶。它参与各种细胞过程,包括细胞周期控制、凋亡和昼夜节律。这个异四聚体激酶包括两个催化亚基,即α或α’,以及两个调节的β亚基。与编码α,或α1亚基(CSNK2A1,基因ID:1457)的紧密相关基因平行物位于染色体20上。这个基因(α2)中的内含子变异可能与南亚人群中的白细胞端粒长度有关。一个相关的转录假基因位于染色体11上。[RefSeq,2017年8月提供]
Related ID:
NCBI:1459
ENSEMBL:ENSG00000070770
HGNC:2459
UNIPROT:P19784
OMIM:115442
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1459
4
12
40200 bp
41.21
23
--
6
26
CSNK2A2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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