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中文小鼠
Gdf3 - growth differentiation factor 3
Alias:
Vgr2
Gdf-3
Vgr-2
ecat9
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这个基因编码一种分泌性的TGF-beta(转化生长因子-beta)超家族蛋白质的配体。这个家族的配体结合各种TGF-beta受体，导致SMAD家族转录因子的招募和激活，从而调控基因表达。编码的前原原蛋白经过蛋白水解加工，生成二硫键连接的同源二聚体的各个亚基。这个蛋白在胚胎发生中具有重要意义，可能参与眼和骨骼发育。缺乏这个基因功能拷贝的小鼠表现出早期胚胎发育缺陷，导致胚胎致死。[RefSeq，2016年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Gdf3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
