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中文人类
CSK - C-terminal Src Kinase
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这个基因编码的蛋白质涉及多个途径，包括调节Src家族激酶。它通过与蛋白酪氨酸磷酸酶非受体类型22（PTPN22）基因编码的蛋白质结合，在T细胞激活中扮演重要角色。这个蛋白质还可以磷酸化多个底物的C端酪氨酸残基，包括SRC原癌基因编码的非受体酪氨酸激酶基因。磷酸化抑制Src家族酪氨酸激酶的激酶活性。这个基因中的内含子多态性（rs34933034）已被发现影响B细胞激活，并与系统性红斑狼疮（SLE）有关。可选的剪接导致多个转录变异体。[RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CSK Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
