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中文小鼠
Gabrg2 - gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
Alias:
gamma2
GABAA-R
Gabrg-2
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这个基因编码一种γ-氨基丁酸（GABA）-A受体亚基，属于配体门控离子通道家族。GABA是成年中枢神经系统中的主要抑制性神经递质，而在发育过程中表现为兴奋性功能。GABA-A受体是五聚体，由来自几个亚基类别的蛋白质组成：α、β、γ、δ和ρ。这个基因编码哺乳动物中三种γ亚基之一，含有苯二氮类药物的结合位点。这个基因的几个突变与癫痫发作有关，遗传敲低与焦虑行为有关。可变剪接导致多个转录变异体。[由RefSeq，2013年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Gabrg2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
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Residues
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Related Mouse Models
Type
Name
MGI
Strain of Origin
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References Literature
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