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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Fut1 - fucosyltransferase 1
Alias:
MFUT-1
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是小鼠中三个编码半乳糖苷2-L-岩藻糖基转移酶的基因之一。这些基因在它们的发育和组织特异性表达方面有所不同。编码的II型膜蛋白锚定在高尔基体中,并控制通过添加α(1,2)键中的末端岩藻糖来创建α(1,2)岩藻糖基化碳水化合物的最终步骤。这个酶是Lewis抗原以及H-抗原,ABH组织血组中A和B抗原的前体的合成所必需的。岩藻糖基化碳水化合物的产物被认为涉及细胞粘附和与微生物的相互作用。这个基因的破坏会损害嗅觉神经的发育和主要嗅球肾小球层的成熟。可变剪接导致编码不同异质体的多种转录变异体。[由RefSeq,2012年12月提供]
Related ID:
NCBI:14343
ENSEMBL:ENSMUSG00000008461
UNIPROT:O09160
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
14343
3
2
3622 bp
42.39
8
9
Fut1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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