人类

DUSP19 - Dual Specificity Phosphatase 19

Alias:
SKRP1
DUSP17
LMWDSP3
TS-DSP1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
双特异性磷酸酶(DUSPs)是I型基于半胱氨酸的蛋白质酪氨酸磷酸酶超家族中的一大异质子群。DUSPs的特点是它们能够去磷酸化酪氨酸和丝氨酸/苏氨酸残基。它们被认为是最重要的信号传导途径的主要调节因子。DUSP19含有共识DUSP C端催化结构域的变异,最后一个丝氨酸残基被丙氨酸替换,并且缺乏DUSPs的MKP(有丝分裂激活蛋白激酶磷酸酶)类中常见的N端CH2结构域(参见MIM 600714)(Patterson等人,2009年总结[PubMed 19228121])。[由OMIM于2009年12月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
4
21262 bp
24.19
12
--
2
7

DUSP19 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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