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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Flt3 - FMS-like tyrosine kinase 3
Alias:
Flk2
Ly72
wmfl
CD135
Flk-2
Flt-3
B230315G04
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使几个功能成为可能,包括磷酸肌醇3-激酶结合活性;蛋白质酪氨酸激酶活性;和泛素蛋白络合物结合活性。涉及几个过程,包括常见的髓样祖细胞增殖;造血;和淋巴细胞增殖。在几个过程的上游或内部发挥作用,包括树突状细胞稳态;造血或淋巴器官发育;和调控细胞因子产生。位于质膜的外侧。在几个结构中表达,包括大脑;背主动脉;免疫系统;生殖系统;和脊髓。用于研究急性髓细胞白血病和幼年髓细胞白血病。这个基因的人类同源物与急性淋巴细胞白血病;急性髓细胞白血病;结直肠癌;肝细胞癌;和前列腺癌有关。与人类的FLT3(fms相关受体酪氨酸激酶3)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14255
ENSEMBL:ENSMUSG00000042817
UNIPROT:Q00342
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14255
4
24
69749 bp
113.50
15
18
Flt3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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