Flot1 - flotillin 1

Predicted to enable ionotropic glutamate receptor binding activity and protease binding activity. Involved in several processes, including positive regulation of cell-cell adhesion mediated by cadherin; positive regulation of cellular component organization; and positive regulation of dopaminergic synaptic transmission. Acts upstream of or within axonogenesis; protein localization to plasma membrane; and regulation of Rho protein signal transduction. Located in caveola; external side of plasma membrane; and sarcolemma. Part of flotillin complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human FLOT1 (flotillin 1). [provided by Alliance of Genome Resources, Apr 2022]