小鼠

Fli1 - Friend leukemia integration 1

Alias:
Sic1
EWSR2
Fli-1
SIC-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及染色质结合活性。参与RNA聚合酶II正向调控转录。在几个过程的上游或内部发挥作用,包括血液循环;巨核细胞发育;以及转录调控,基于DNA模板。位于细胞核中。在几个结构中表达,包括消化系统;鳃弓;心血管系统;生殖泌尿系统;以及神经系统。用于研究系统性硬皮病。该基因的人类同源物与血小板疾病和血小板减少症有关。与人类FLI1(Fli-1原癌基因,ETS转录因子)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
4
9
120793 bp
51.00
13
10

Fli1 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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