Enables keratin filament binding activity. A structural constituent of skin epidermis. Acts upstream of or within epidermis development; establishment of skin barrier; and intermediate filament organization. Located in cornified envelope and keratohyalin granule. Is expressed in eyelid epithelium; foregut; metapodial pad epidermis; and skin. Used to study atopic dermatitis 2. [provided by Alliance of Genome Resources, Apr 2022]