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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Foxc2 - forkhead box C2
Alias:
Mfh1
Fkh14
MFH-1
Hfhbf3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录激活活性;DNA结合转录因子活性,特异性为RNA聚合酶II;以及启动子特异性染色质结合活性。参与多种过程,包括正向调控血管新生中的芽生血管细胞迁移;正向调控血管伤口愈合;以及调控基于DNA的转录。在多个过程的上游或内部发挥作用,包括动物器官发育;细胞表面受体信号通路;以及血管发育。预测位于核体中。在多个结构中表达,包括心血管系统;中枢神经系统;胚胎间充质;肢体长骨;和感觉器官。该基因的人类同源物涉及几种疾病,包括淋巴水肿;淋巴水肿-毛状分支综合症;肥胖症;上睑下垂;和2型糖尿病。与人类FOXC2(翼状翅盒C2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14234
ENSEMBL:ENSMUSG00000046714
UNIPROT:Q61850
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14234
1
1
2725 bp
52.87
10
8
Foxc2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Cell-specific RNA expression
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Acting
Regulation
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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