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中文小鼠
Smc2 - structural maintenance of chromosomes 2
Alias:
CAPE
CAP-E
Fin16
SMC-2
Smc2l1
5730502P04Rik
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这个基因编码的蛋白质是condensin I和condensin II复合物的成分，并与结构维护染色体4（Smc4）形成异二聚体。这个异二聚体是两种复合物的催化亚基，并参与几个过程，包括有丝分裂和减数分裂期间的染色体浓缩、有丝分裂和减数分裂期间的cohesin去除以及单链断裂（SSB）修复。这个基因的表达减少会导致有丝分裂和减数分裂期间染色体分离缺陷，在胚胎干细胞中观察到更严重的缺陷。可选的剪接导致多个转录变异体。[RefSeq，2014年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Smc2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
