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Fasl - Fas ligand (TNF superfamily, member 6)

Alias:
gld
CD178
CD95L
Fas-L
Faslg
CD95-L
Tnfsf6
Tnlg1a
APT1LG1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够死亡受体结合活性和肿瘤坏死因子受体结合活性。通过死亡结构域受体和视网膜细胞程序性细胞死亡在外在凋亡信号通路的上游或内部起作用。位于质膜外侧。在几个结构中表达,包括消化系统;大脑;血淋巴样系统腺体;生殖系统;和外胚层。用于研究自身免疫性淋巴增生综合症和1型糖尿病。该基因的人类同源物涉及几种疾病,包括胆管癌;慢性髓性白血病;糖尿病(多种);胰腺癌(多种);和先兆子痫(多种)。与人类FASLG(Fas配体)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
4
7805 bp
31.44
12
16

Fasl Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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