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中文小鼠
Fap - fibroblast activation protein
Alias:
SIMP
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这个基因属于丝氨酸蛋白酶家族。编码的蛋白质是一种在肿瘤相关成纤维细胞和平滑肌细胞中特异地表达的可诱导性细胞表面结合糖蛋白，并具有蛋白酶和明胶酶活性。该蛋白质在细胞外基质(ECM)的重塑中发挥作用，可能影响肿瘤发生和组织修复。文献中描述了该基因的可变剪接转录变异体（PMID 9139873），但这些变异体的完整序列尚未可用。[由RefSeq，2013年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Fap Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
