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Ptk2 - PTK2 protein tyrosine kinase 2

Alias:
FAK
FRNK
Fadk
FADK 1
p125FAK
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有非跨膜蛋白酪氨酸激酶活性。参与细胞群增殖的正调控;泛素依赖性蛋白质分解过程的正调控;以及蛋白质磷酸化。在几个过程的上游或内部发挥作用,包括血管形态发生;神经元生成;以及肽基酪氨酸自磷酸化。位于几个细胞组件中,包括顶质膜;粘着斑;和膜下薄层。在几个结构中表达,包括消化系统;中枢神经系统;眼睛;生殖泌尿系统;和卵黄囊。该基因的人类同源物涉及平滑肌瘤;肺小细胞癌;和肺高血压。与人类PTK2(蛋白酪氨酸激酶2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
48
32
220242 bp
119.24
18
48

Ptk2 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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