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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ptk2 - PTK2 protein tyrosine kinase 2
Alias:
FAK
FRNK
Fadk
FADK 1
p125FAK
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有非跨膜蛋白酪氨酸激酶活性。参与细胞群增殖的正调控;泛素依赖性蛋白质分解过程的正调控;以及蛋白质磷酸化。在几个过程的上游或内部发挥作用,包括血管形态发生;神经元生成;以及肽基酪氨酸自磷酸化。位于几个细胞组件中,包括顶质膜;粘着斑;和膜下薄层。在几个结构中表达,包括消化系统;中枢神经系统;眼睛;生殖泌尿系统;和卵黄囊。该基因的人类同源物涉及平滑肌瘤;肺小细胞癌;和肺高血压。与人类PTK2(蛋白酪氨酸激酶2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14083
ENSEMBL:ENSMUSG00000022607
UNIPROT:P34152
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14083
48
32
220242 bp
119.24
18
48
Ptk2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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