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中文小鼠
F9 - coagulation factor IX
Alias:
Cf9
Cf-9
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这个基因编码一种依赖于维生素K的天冬氨酸蛋白酶，在血液凝固的内在途径中扮演关键角色。编码的蛋白质是一种无活性的酶原，通过凝血因子XIa激活生成因子IXa，一种包含重链和轻链的异源二聚体。与因子VIII、膜磷脂和钙离子结合，因子IXa切割无活性的酶原因子X，生成有活性的因子Xa。小鼠中这个基因的遗传缺失导致严重的出血表型。这个基因的可变剪接导致多个转录变异体。[由RefSeq，2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
F9 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
