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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
F7 - coagulation factor VII
Alias:
Cf7
FVII
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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References Literature
这个基因编码一种依赖于维生素K的天冬氨酸蛋白酶,在血液凝固的外部途径中扮演关键角色。与组织因子III(TF III)接触后,编码的蛋白质形成一个被称为TF-FVIIa的激活复合物,启动涉及其他凝血因子的凝血级联反应,最终导致纤维蛋白凝块。在鼠中,编码蛋白的完全缺乏导致围产期死亡,原因是正常血管中的出血。[RefSeq,2015年4月提供]
Related ID:
NCBI:14068
ENSEMBL:ENSMUSG00000031443
UNIPROT:P70375
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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14068
1
8
10311 bp
50.28
8
10
F7 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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