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中文小鼠
F3 - coagulation factor III
Alias:
TF
Cf3
Cf-3
CD142
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这个基因编码一个膜结合糖蛋白，在血管损伤后形成血液凝固过程的主要生理启动子。编码的蛋白质与凝血因子VIIa结合，然后形成的复合物催化凝血因子IX和X的蛋白水解激活。缺乏编码蛋白质的小鼠在子宫内因胚外和胚内血管的大出血而死亡。小鼠中编码蛋白质的严重缺乏导致子宫内稳态受损，由于自发的致命出血和心肌纤维化而缩短寿命。[RefSeq,2015年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
F3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
